Clinical safety of the usage of materials for implantation surgery based on titanium and its alloys according to the biocompatibility indexes
https://doi.org/10.33667/2782-4101-2024-1-4-9
Abstract
Biocompatibility is one of the most important characteristics of materials for implantation. It has been scientifically confirmed that the physical and chemical properties of the surface of metal implants or their elements can have an impact on clinical safety. The structure of the material (porosity, smoothness, geometry) can influence its incorporation into surrounding tissues. This requires conducting experiments with a longer contact interval of the tested materials under in vivo conditions.
About the Authors
Al. Al. DolgalevRussian Federation
Alexander Alexandrovich Dolgalev, MD, Professor
Department of General Dentistry and Pediatric Dentistry
Stavropol
M. S. Vorobyov
Russian Federation
Maxim Sergeevich Vorobyov, Doctor of Technical Sciences, Leading Researcher
Tomsk
N. A. Prokopenko
Russian Federation
Nikita Andreevich Prokopenko, Junior Researcher
Tomsk
D. Z. Choniashvili
Russian Federation
David Zurabovich Choniashvili, Candidate of Medical Sciences, Associate Professor, Dean, Chief physician
Department of Therapeutic, Surgical and Pediatric Dentistry with a course in Implantology, reconstructive Surgery of the oral cavity, pediatric CHLH; Faculty of Medicine
Vladikavkaz
G. K. Gezuev
Russian Federation
Gimalai Kazbekovich Gezuyev, freelance orthopedic dentist, dental surgeon
Chechen Republic; Grozny
V. M. Avanisyan
Russian Federation
Vazgen Mikhailovich Avanisyan, prosthodontist, Assistant
Department of Organization of Dental Care, Management and Prevention of Dental Diseases
Stavropol
S. I. Piskov
Russian Federation
Sergey Ivanovich Piskov, PhD, Leading Researcher
Faculty of Medicine and Biology; Interdepartmental Scientific and Educational Laboratory of Experimental Immunomorphology, Immunopathology and Immunobiotechnology
Stavropo
I. V. Rzhepakovsky
Russian Federation
Igor Vladimirovich Rzhepakovsky, PhD, Associate Professor, leading researcher
Faculty of Medicine and Biology; Interdepartmental Scientific and Educational Laboratory of Experimental Immunomorphology, Immunopathology and Immunobiotechnology
Stavropol
References
1. Botasheva V.S., Dolgalev A.A., Christoforando D.Yu., Garaza S.N., Vorobyev M.S., Choniashvili D.Z., Sadovsky V.V., Avanisyan V.M., Gezuyev G.K. Study of biocompatibility and angiogenesis in vivo on a model of chorioallantoid shell of chicken embryo samples for implantation surgery based on titanium and its alloys // Medical Alphabet. 2024;(28):107–111.
2. Baiguera, S., Macchiarini, P., & Ribatti, D. (2012). Chorioallantoic membrane for in vivo investigation of tissue-engineered construct biocompatibility. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 100(5), 1425-1434. DOI: 10.1002/jbm.b.32653.
3. Breban-Schwarzkopf D., Chioibas R., Macasoi I., Bolintineanu S., Marcovici I., Draghici & Szuhanek C. (2024). Comprehensive in vitro and in ovo assessment of cytotoxicity: Unraveling the impact of sodium fluoride, xylitol, and their synergistic associations in dental products. Biomolecules and Biomedicine, 24(4), 923-938. DOI: 10.17305/bb.2024.10181.
4. Fabricky M.M., Gabor A.G., Milutinovici R.A., Watz C.G., Avram Ş., Drăghici G., ... & Sinescu C. (2021). Scaffold-Type Structure Dental Ceramics with Different Compositions Evaluated through Physicochemical Characteristics and Biosecurity Profiles. Materials, 14(9), 2266.
5. Fernandes P.F., Grenho L., Fernandes M.H., Sampaio-Fernandes J.C., & Gomes P.S. (2023). Microgap and bacterial microleakage during the osseointegration period: An in vitro assessment of the cover screw and healing abutment in a platform-switched implant system. The Journal of Prosthetic Dentistry, 130(1), 87–95.
6. Huang Y., Huang C., Tsai P. et al. Three-Dimensional Printed Porous Titanium Screw with Bioactive Surface Modification for Bone – Tendon Healing: A Rabbit Animal Model // Int. J. Mol. Sci. 2020. Vol. 21. N. 10. P. 3628.
7. Kaur M., Singh K. Review on titanium and titanium based alloys as biomaterials for orthopaedic applications // Materials Science and Engineering C. 2019. Vol. 102. N. 9. P. 844–862. DOI: 10.1016/j.msec.2019.04.064.
8. Murr L.E. Metallurgy principles applied to powder bed fusion 3D printing/additive manufacturing of personalized and optimized metal and alloy biomedical implants : an overview // J. Mater. Res. Technol. 2020. Vol. 9. N. 1. P. 1087–1103.
9. Yan R., Li J., Wu Q. et al. Trace Element-Augmented Titanium Implant With Targeted Angiogenesis and Enhanced Osseointegration in Osteoporotic Rats // Frontiers in Chemistry. 2022. Vol. 10. DOI: 10.3389/fchem.2022.839062.
10. Zdziennicka J., Wessely-Szponder J., Starobrat G. et al. The Effect of Neutrophil-Derived Products on the Function of Leukocytes Obtained after Titanium Implantation in the Ovine Model // Animals (Basel). 2021. Vol. 11. N. 12. P. 3569–3586.
11. Shugurov V.V., Koval N.N., Krysina O.V., Prokopenko N.A. QUINTA equipment for ion-plasma modification of materials and products surface and vacuum arc plasma-assisted deposition of coatings // Journal of Physics: Conference Series. 2019. Vol. 1393, No. 012131. doi: 10.1088/1742-6596/1393/1/012131
Review
For citations:
Dolgalev A.A., Vorobyov M.S., Prokopenko N.A., Choniashvili D.Z., Gezuev G.K., Avanisyan V.M., Piskov S.I., Rzhepakovsky I.V. Clinical safety of the usage of materials for implantation surgery based on titanium and its alloys according to the biocompatibility indexes. International journal of Innovative Medicine. 2024;(1):4-9. https://doi.org/10.33667/2782-4101-2024-1-4-9